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nPULSE

Nanosecond Pulsed Field Ablation (nPULSE) for Thyroid Nodules

Nanosecond pulsed field ablation (nPULSE) is an advanced, non-thermal treatment designed for precise ablation of selected thyroid nodules while preserving surrounding healthy tissue. This innovative technology uses ultra-short electrical pulses to disrupt targeted cells at a microscopic level without relying on heat, helping minimize injury to nearby nerves, blood vessels, and normal thyroid tissue. Because nPULSE is non-thermal, it offers a unique approach for treating nodules located near sensitive structures in the neck where heat-based treatments may be less ideal. It is a minimally invasive procedure that can provide effective treatment with little discomfort, no surgical scar, and a rapid recovery.
nPULSE

How nPULSE Works

During the procedure, a small probe is carefully placed into the thyroid nodule using real-time ultrasound guidance. Local anesthesia is used to keep you comfortable. The device then delivers precisely controlled nanosecond electrical pulses that create tiny openings in the targeted cell membranes, leading to destruction of the abnormal tissue while sparing surrounding structures. Over time, the body naturally clears the treated cells and the nodule gradually shrinks.

What are the Benefits of nPULSE

  • Non-thermal treatment with no heat damage
  • Precise targeting of abnormal tissue
  • Helps preserve nearby nerves, vessels, and healthy thyroid tissue
  • No surgical incision or scar
  • Minimal discomfort and quick recovery
  • Outpatient procedure with local anesthesia
  • Rapid return to normal activities
  • Preserves thyroid function whenever possible

What to Expect

nPULSE is typically performed in the office or outpatient setting. Procedure time depends on the size and location of the nodule but is generally brief. Most patients experience minimal downtime and return to regular activities within a day or two. Mild temporary soreness or swelling may occur after treatment.

Is nPULSE Right for You?

nPULSE may be considered for patients with:
  • Selected benign thyroid nodules causing symptoms or cosmetic concerns
  • Nodules located near important neck structures
  • Patients seeking a non-surgical treatment option
  • Individuals who want to avoid scarring or lengthy recovery
A consultation, ultrasound evaluation, and review of biopsy results can help determine whether nPULSE is the best treatment option for you.

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